METHADONE RESTLESS LEGS FUNDAMENTALS EXPLAINED

CYP2B6 is The main CYP enzyme involved in the metabolism of S-methadone and also to an extent, R-methadone. The expression of CYP2B6Quite a few SNPs impacting methadone pharmacodynamics together with pharmacokinetics are explained. The purpose of this review is to supply a narrative overview of literature related to pharmacogenomics of methadone.A